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New hypothesis emerges to explain mysterious hepatitis cases in kids

Accepted submission by Freeman at 2022-07-26 16:00:30 from the speculation dept.
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https://arstechnica.com/science/2022/07/new-hypothesis-emerges-to-explain-mysterious-hepatitis-cases-in-kids/ [arstechnica.com]

Researchers in the United Kingdom have come up with the most detailed, complex hypothesis yet to explain the burst of mysterious cases of liver inflammation—aka hepatitis—in young children, which has troubled medical experts worldwide for several months.
[...]
In two new reports, UK researchers offer a fresh hypothesis that may be the clearest but most complex explanation. Their data suggests that the cases may arise from a co-infection of two different viruses—one of which could be an adenovirus and the other a hitchhiking virus—in children who also happen to have a specific genetic predisposition to hepatitis.

In one of the new studies [medrxiv.org], looking at nine early cases in Scotland, researchers found that all nine children were infected with adeno-associated virus 2 (AAV2). This is a small, non-enveloped DNA virus in the Dependoparvovirus genus. It can only replicate in the presence of another virus, often an adenovirus but also some herpesviruses. As such, it tends to travel with adenovirus infections, which spiked in Scotland when the puzzling hepatitis cases arose.

Previously:
Sixth Child in US Dies of Unexplained Hepatitis as Global Cases Top 600 [soylentnews.org] - May 24th 2022
CDC Raises Alarm of Mysterious Hepatitis Cases in Kids; 2 States Report Cases [soylentnews.org] - April 22nd 2022


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