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Synthetics now killing more people than prescription opioids, report says
Synthetic opioids such as fentanyl have overtaken prescription opioids as the No. 1 killer in the opioid epidemic, according to a new report.
The report, published Tuesday in the journal JAMA [DOI: 10.1001/jama.2018.2844] [DX], calculated the number and percentage of synthetic opioid-related overdose deaths in the United States between 2010 and 2016 using death certificates from the National Vital Statistics System. The researchers found that about 46% of the 42,249 opioid-related overdose deaths in 2016 involved synthetic opioids such as fentanyl, while 40% involved prescription drugs.
That's more than a three-fold increase in the presence of synthetic opioids from 2010, when synthetic drugs were involved in approximately 14% of opioid-overdose deaths.
Related: Heroin, Fentanyl? Meh: Carfentanil is the Latest Killer Opioid
Study Finds Stark Increase in Opioid-Related Admissions, Deaths in Nation's ICUs
U.S. Life Expectancy Continues to Decline Due to Opioid Crisis
Purdue Pharma to Cut Sales Force, Stop Marketing Opioids to Doctors
The More Opioids Doctors Prescribe, the More Money They Make
Two More Studies Link Access to Cannabis to Lower Use of Opioids
(Score: 3, Insightful) by Gaaark on Wednesday May 02 2018, @01:28AM (2 children)
I guess there's too much profit in synthetics.
https://www.youtube.com/watch?v=OfIuSUvJ4jw [youtube.com]
--- Please remind me if I haven't been civil to you: I'm channeling MDC. ---Gaaark 2.0 ---
(Score: -1, Spam) by Anonymous Coward on Wednesday May 02 2018, @01:36AM (1 child)
http://searchnut.com/?ncn=fd804377d4c5835ebe5cd93b11980ae41525224992&sb=1&pt=2&qs=&st=I+guess+there%27s+too+much+profit+in+synthetics. [searchnut.com]
(Score: 0) by Anonymous Coward on Friday May 04 2018, @01:11AM
The stupid aren't dying fast or often enough. We need stronger drugs.
(Score: 2, Insightful) by Anonymous Coward on Wednesday May 02 2018, @01:43AM (15 children)
You don't have to take any of these drugs.
It comes down to personal responsibility, regardless of whether the drugs are legal or not.
Respect yourself enough not to do bad things to yourself. That also goes for tobacco and alcohol.
( cue the replies from people who don't understand that all of life is the summation of choices we make for ourselves ; these people would have you believe that someone else is responsible for stupid things people do to themselves. )
(Score: 3, Funny) by LoRdTAW on Wednesday May 02 2018, @02:06AM
Man you are so missing out.
(Score: 5, Insightful) by sjames on Wednesday May 02 2018, @02:11AM (4 children)
You DO know that many people who get addicted start out taking opoids for legitimate medical reasons, yes?
(Score: 5, Informative) by Runaway1956 on Wednesday May 02 2018, @02:31AM (3 children)
And, we also need to point out that "many people" is not "all people", or even "most people". Those addicts with whom I am personally acquainted all CHOSE to get high that first time. One brother in law is a possible exception - he's had health problems all his life, including being a bleeder. He *maybe* accidentally got addicted to the stuff he abuses. None of my other immediate acquaintances were addicted while under a doctor's care.
The idea of getting addicted while undergoing treatment for life threatening illness/injury has always existed. But, only in very recent years has it become a wide ranging, very serious problem. Washington listened to some lobbyist's bullshit, and relaxed regulations on opioids, and within a decade, we had an opioid crisis.
I have already related how I was given morphine by an ambulance crew, when there was simply no need for morphine. Pain? What pain? If I were in pain, I'm pretty damned sure that I would have known all about it. I can recall all of my injuries from six decades of life that involved severe pain. I exclude the first year or two - I DO NOT remember breaking my arm as a baby.
Maybe we need to do some research, to learn why people get high the first time. I suspect that peer pressure plays a greater role than just about anything else.
(Score: 3, Interesting) by sjames on Wednesday May 02 2018, @04:31AM (2 children)
Sure, many people are the author of their own addiction, but I was replying to a post that offered no exceptions. I pointed out that there ARE exceptions.
The problem is many fold. Part of it is that the restrictions are too tight. Doctors cut patients off cold turkey so the DEA doesn't breathe down their necks and then the addicted patient has little to no way to deal with it that doesn't involve admitting to a crime. The FDA dropped the ball in a few cases letting manufacturers get away with claiming that some of the riskier opioids were practically risk free.
And part of it is just fluffing the figures. The hospice care patient that ODed 20 years ago would be said to have died of whatever terminal condition was causing all the pain in the first place. Now it's called an opioid death.
As for your case in the ambulance, there are possible explanations. First, pain doesn't always set in right away. They might have anticipated that it was about to get really bad. Two, sometimes even when you aren't experiencing the pain consciously, there is an undesirable physiological reaction that opioids might stop. There may be others, but not knowing the exact circumstances it's hard to say. I know I once got quite a dose of demerol in spite of not being in much pain so the surgeon could get my muscles to relax enough to reattach a tendon.
If the feds were serious about actually fixing the problem there would be a push to legalize at least medical marijuana since it is known to reduce the need for opioids.
(Score: 2) by frojack on Wednesday May 02 2018, @06:54AM (1 child)
Ah, what planet have you been vacationing on where you haven't heard that the majority of states already have legal medical marijuana?
No, you are mistaken. I've always had this sig.
(Score: 3, Informative) by sjames on Wednesday May 02 2018, @07:13AM
I said the *FEDS*. On what planet are the feds anything but entrenched against legalization?
(Score: 2, Insightful) by Runaway1956 on Wednesday May 02 2018, @02:20AM (3 children)
Are you serious? A person isn't forced to take this shit?
All these years, I thought the cartels sent high squads into the inner cities, kidnapped unsuspecting citizens, and shot them full of addictive drugs.
Are you telling me that's not how things are?
(Score: -1) by fakefuck39 on Wednesday May 02 2018, @04:44AM (2 children)
For some reason I see this retarded comment and have this weird feeling of "oh, this is one of those regular people who thinks they're smart. Finally figured out why. this thyme the guy reads the 1st line, pretends the rest of the post doesn't exist. How dumb do you have to be. Then I finally remembered. This dude, a few months ago, was confused about the difference between an atom and a molecule. I gave the example of Splenda and elemental Cl, table salt and Cl, nothing. Still kept saying quarts is a transparent metal or some shit like that. The true definition of faggot. Have you met cdreimer from greenville? kick the bit bucket buddy, kick that shit with your foot.
(Score: 0) by Anonymous Coward on Friday May 04 2018, @01:13AM (1 child)
"thyme"
(Score: -1) by fakefuck39 on Saturday May 05 2018, @11:54AM
that's the only error you noticed? you need to learn some grammar. I have this game I play here - it's called setting up people who think they're smart so they provide me with entertanement while I'm taking a shit. or, you know, I could not know how to spell "time" - that's certainly a possibility too. thanks for letting me know.
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @06:22AM
It's so easy to be smug until it isn't.
First, you've got people who get seriously injured and become
physically and/or psychologically dependent. They didn't choose
get in a car accident, or have severe arthritis, or slip a disk. It just
happened. Next thing you know the pills run out and they go through
physical withdrawal. This is how too many people find out that they're
prone to addiction.
Secondly, some people are more prone than others. There
are probably foods you like and don't like. Why? Hard to say.
Same deal with drugs. Me, personally, I've had morphine once several years ago.
It was a really good pain killer. That's it. I actually didn't like the
rush at all. I liked not being in severe pain; but that's it. Other people?
They get that first hit and it's like they found God.
Are there people who are jackasses who tried these things
just for thrills and became addicts? You bet. That's not everybody
though.
(Score: 2) by c0lo on Wednesday May 02 2018, @09:38AM (2 children)
How am I responsible for the stupidity of your comment and how can I chose to avoid it without leaving S/N?
'cause certainly your comment killed some of my neurons.
https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @05:02PM (1 child)
Can't handle the political ideologies that ignore reality in favor of sound-bites that make people feel better about their "fuck you got mine" mentality? Sheesh, what a little emotional sand flea you are!!/s
(Score: 2) by c0lo on Wednesday May 02 2018, @10:00PM
But of course you were going to miss the point in favour of an ad hominem.
https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford
(Score: 2) by DeathMonkey on Wednesday May 02 2018, @06:05PM
You don't have to take any of these drugs.
Sometimes they don't even know they are!
Prince being a recent example. [latimes.com]
(Score: 4, Interesting) by sjames on Wednesday May 02 2018, @01:58AM (9 children)
Fentanyl is both synthetic and prescription. What in the hell are they trying to say?
So if a terminal patient receiving palliative care dies when they go over the threshold with their prescribed fentanyl in an effort to be fairly comfortable or literally die trying, do they count that as a death due to synthetic opoid or prescription? or do they put a hash in both columns for that one?
(Score: 3, Insightful) by The Mighty Buzzard on Wednesday May 02 2018, @02:00AM (8 children)
This is just what happens when you let journalists cover things that take even a modicum of intelligence to grasp.
My rights don't end where your fear begins.
(Score: 2) by takyon on Wednesday May 02 2018, @02:16AM (7 children)
Here's the abstract:
[SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
(Score: 1, Flamebait) by The Mighty Buzzard on Wednesday May 02 2018, @02:28AM (6 children)
Right. This is not the first time we've discussed a journalist looking at an abstract and going "uh, duh?" though. Not even the first time this week.
My rights don't end where your fear begins.
(Score: 2) by takyon on Wednesday May 02 2018, @02:44AM (3 children)
Eh? The abstract basically uses the same "synthetic opioid vs. prescription opioid" language as the CNN article.
[SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
(Score: 1, Flamebait) by The Mighty Buzzard on Wednesday May 02 2018, @03:00AM (2 children)
A) I can see how that one sentence could be read that way but it's not the only way it could be read.
B) Having half a clue what they're reporting on so they could catch obvious errors like that would be rather nice.
Yall Eds would certainly get your chops busted for making that mistake. I don't see why professional journalists that get paid actual money to do the job should get a pass.
My rights don't end where your fear begins.
(Score: 4, Informative) by arslan on Wednesday May 02 2018, @05:02AM (1 child)
Eh? They get paid to do stories? I thought they get paid to shill whatever political propaganda their outfit is funded by. The stories are just to pass time and make it look like they're a real news outlet.
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @03:04PM
yeah.
saying synthetic is different than prescription sounds more like they are saying propaganda than any specific differences.
They do the same thing.
Perhaps they meant to say "drugs not providing revenue to the pharmaceutical industry"
(Score: 2) by realDonaldTrump on Wednesday May 02 2018, @07:59AM (1 child)
You're not an Editor. And that's too bad. Because you're very good at seeing the bad & Fake stories!!!
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @04:50PM
TMB everyone, endorsed by a fake Trump. So fitting!
(Score: 5, Insightful) by leftover on Wednesday May 02 2018, @02:35AM (18 children)
Here in Ohio the "opioid epidemic" is everyday news, reported in a manner that is both ignorant and sensationalist. Solid research showing the underlying cause to be a loss of hope is completely ignored, apparently too abstract for the self-styled journalists to handle. Much easier to continue building on "Reefer Madness" delusions than to say our socio-economic structure is FUBAR. Pardon me for not being aloof/detached, this has already hit my family and friends. Working hard and skillfully is worth nothing because "all value is created on Wall Street". Nurturing the land and environment is passe because all resources are to be "exploited" for short-term gain.
Just how much reason do people need to discard for this tripe to seem acceptable? What will bring an end to it?
Bent, folded, spindled, and mutilated.
(Score: 3, Insightful) by PartTimeZombie on Wednesday May 02 2018, @02:46AM (2 children)
Loss of hope as a reason for a drug epidemic just sounds awful.
I knew things were tough in parts of the US, but I didn't think it was that bad.
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @04:16AM
Everything's been characterized bad by the media since Trump was elected.
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @05:32AM
You can blame it on Obama. He gave us hope, then took a shit in our hands and called it change. He also kept pumping afghan heroin into the US, after Bush sent so many young people over there to get fucked up physically and mentally.
(Score: 2, Interesting) by khallow on Wednesday May 02 2018, @04:24AM (11 children)
Who's saying that? I googled [google.com] the term in quotes and a previous post [google.com] by you, leftover, is the only and I do mean only reference to that particular quote. Maybe if you don't like that idea, then don't believe in it, right?
Moving on:
And yet there's a hell of a lot more nurturing of land and environment now than there was in the days when corporate greed was supposedly not so bad. In the US, which has Wall Street, we have more park acreage, stronger environmental laws, and a lot more municipal parks.
In other words, we have here the usual Chicken Little narrative. But in reality the US is doing as well as it ever has, with better care of environment and other factors you claim to care about.
So let me present some contrary factors for your consideration. What is more important to you: Protecting US labor or creating a more valuable labor force? Being able to afford a home or increasing the value of existing homes? Making it easy for people to enter a field of labor or to protect the wages of existing labor from competition? Honoring pension and health care benefits that the elder voted for themselves or the wages of the young (with young being anyone under retirement age)?
Opoid abuse is just the latest prescription drug abuse fad. Before that we had things like valium and steroids which were also massively abused (and heroin, opium, aspirin, etc before that). There's always been people lacking hope or wanting a little extra. Let us also keep in mind that the primary cause of lack of hope, inevitable death in a few decades due to aging, is still with us. I'd love to get rid of that particular socio-economic problem, but doesn't look to be in the cards during my lifetime.
(Score: 2) by captain normal on Wednesday May 02 2018, @05:25AM (1 child)
People actually abused aspirin? Oh my God! I've been taking that shit since I was a wee tyke. Always patted myself on the back because I wasn't into hard drugs. Sure maybe I did some MaryJane in college and had a bit of beer and sometime binged on whisky and/or tequila and vodka...now into Zinfandel (now that's some heavy stuff), but I've always fallen back to aspirin---the sure hangover cure and soreness cure from too much hard labor, surfing, handball, city league basketball or hard core competitive sailing. I don't do it all the time but only when I think I need it....My god...I must be an aspirin addict!
On the other hand you do make a couple of good points. Especially the 4th paragraph. Good questions.
Everyone is entitled to his own opinion, but not to his own facts"- --Daniel Patrick Moynihan--
(Score: 1) by khallow on Wednesday May 02 2018, @05:52AM
(Score: 2) by shortscreen on Wednesday May 02 2018, @06:17AM (2 children)
I recall that you have made posts with a similar theme before. It's definitely something to think about. Why do people feel like everything is going to shit, if quantitative measures (eg. violent crime) show the opposite of that? Maybe there are other factors to consider: levels of personal and public debt, inequality (perceived or actual), Orwellian surveillance and doublespeak, "if it bleeds it leads"
(Score: 2, Interesting) by khallow on Wednesday May 02 2018, @07:46AM
For example, when you're having to compete for the same jobs with a variety of foreign workers who often worked for an order of magnitude less, that puts stress on you to do better than the alternatives. Often that didn't happen and that work ended up on distant shores. The baby boomer phenomenon also created a one-time economic windfall (growing wealth from real estate) that isn't easily duplicated.
The second point is that a vast number of political decisions serve to protect the interest of existing voters rather than invest in the future. For example, in areas with good economic conditions, there is a universal trend towards protection of existing real estate over creation of more. Homes in particular have grown so expensive that they inadvertently serve to exclude the less well-off from the better economic areas. When we create a system where the home becomes a store of value, perpetually increasing in value via policy and contrived economics, we create a situation where it becomes very expensive to live in a home.
If I want to move to a place with better work opportunities, odds are good that I'll have to pay a lot more for my housing, even if I rent instead of buying a home. That's a big obstacle to economic migration in the US.
Similarly, there have been many, many schemes at the state and local levels to license businesses and occupations. Where the licensing isn't onerous, this can result in better quality. But where it is onerous, it results in rent seeking protectionism where whole sectors of commerce are protected from competition to the detriment of everyone else.
In a typical two-parent family where both parents work, if one parent works in a restricted sector (for example, K-12 education) where crossing state lines can result in substantial training or licensing requirements in order to preserve the ability to work, then that becomes yet another an obstacle to migration to better locales. You get stories like where one parent has to turn down a nice job because the other parent can't get work there.
Finally, there's plenty of examples of short-sighted decisions about future generations who can't vote yet. Not much point to a pension system like Social Security that delivers less value than it soaks up in taxes for people younger than about 60. Or the world famous, inflated US health care. Or all the usual political messes that go on.
The third point is an important one. Sometimes people don't know any better. Information can cure that usually. But sometimes they perceive things a certain way because they are invested in that viewpoint. It can be really hard to convince someone when they really want to believe in a false story. I believe this is a large part of the problem, that people want to believe that things are getting worse, that greed or evil is ascendant, etc in order that they may be the savior of their story. So what should we do about these negative perceptions of our world when many of them are merely acting out private or ideological stories that don't have much to do with us? With that, I focus on the weak spots of those stories. Maybe they have an obsession to defend the acts of the current Venezuelan government. Maybe they have to insist that any Muslim migrant is guilty of genocide or other hideous crimes. At some point, you can get them into one or more untenable positions where they have to advocate some monumentally irrational or diabolical act to defend their narratives. That's when you get them.
(Score: 2, Interesting) by Anonymous Coward on Wednesday May 02 2018, @04:17PM
As someone who left my home region because of the economy - it's because "quantitative measures" are usually averages across the entire nation, and by population. Most of the population lives in very small dots on the map, so unless you live in one of those dots it's not going to reflect your own reality.
Just as my personal example... saying "Look! The economy is great because unemployment is 4%!" means nothing to the place I grew up because unemployment is actually between 8-10% unless you drive 100 miles. Everyone you see and interact with on a regular basis doesn't live in a place where unemployment is 4%. We don't have violent crime as a problem, so why would we care if it's going down from 2 instances per year to 1? When it's that low it's just noise, it means nothing.
I don't really have a feel on the other two things you mentioned, because everyone is poor out there and we know that debt is to be avoided if possible. If you take a student loan, you by default leave the region because you can't find a job to pay for it where you grew up. Brain drain is a massive problem - but not for the cities, because that's where they are being drained to.
If I have to drive 300 miles to find a place where the measures are actually close to the measurement, it's not very good to use for quality-of-life. And if people keep using them to "prove" that things are good, like federal politicians do, I'm going to treat them as a untrustworthy because they clearly live in different reality than me. I'm not going to believe you necessarily even if you are telling the truth.
(Score: 2) by c0lo on Wednesday May 02 2018, @09:54AM (3 children)
And are you very sure that all of the above are 'true dichotomies'?
Because they may be dichotomies only because you take for granted some assumptions one shouldn't.
Why the pension/ heath care benefits of the elderly need to compete with the wages of the young?
Why does the price of homes need to increase over time? After all, when I buy many other kinds of assets, the value of them go down over time.
https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford
(Score: 1) by khallow on Wednesday May 02 2018, @02:10PM (2 children)
That would be irrelevant.
No matter the answer to the questions (which I incidentally think aren't worth answering, being both irrelevant and not that insightful), the US has conflicts implied by my questions which could go a long ways to explaining the stresses that result in opioid drug abuse.
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @02:49PM (1 child)
Smoke and mirrors, eh?
Confuse them, throw them off the track with some 'questions', make them implicitly accept the status quo by accepting those questions as valid.
Otherwise they may see there are other ways beside opioids.
(Score: 1) by khallow on Wednesday May 02 2018, @09:45PM
You have a point there. C0lo never did come up with an example illustrating the absence of "true dichotomies". It was a criticism brought up without context.
I merely focused on the other flaw namely that one doesn't need a perfect dichotomy. All one needs is large trade offs between the choices.
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @04:53PM (1 child)
You really are a brainwashed fool. At least you have a few semi-decent points in there, but mostly your a corporate apologist who supports the on going destruction of our environment. Burn in hell you piece of trash.
(Score: 1) by khallow on Wednesday May 02 2018, @09:47PM
Since there is no ongoing destruction of the US environment (it has actually gotten much better over the past 50 years), I rest my case. Go bug someone else with your idiocy.
(Score: 4, Funny) by c0lo on Wednesday May 02 2018, @09:45AM
Solving the problem specifically for the people of Ohio is pretty easy: just relocate the entire population in other states and, voila, no more alarmist 'opiod epidemic' news in Ohio.
https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @03:20PM (1 child)
Only she's also drunk the Reefer Madness kool-aid, and while being abused in the workplace as an effective wage slave (mandatory 8 hour shifts that are defacto mandatory 12 hour shifts) and a rehire policy that only allows you to reapply after 3 years. Meaning nobody can jump ship unless they are sure the replacement job won't lay them off/fire them in less than 3 years.
America, especially the midwest from her stories, has some really fucked up areas without job opportunities that are effectively a modern form of slavery. Getting out of there requires a strong network of friends willing to line you up with a job and a place in a better work environment, or you yourself being driven enough to do the legwork of job hunting, and finding time to make interviews, to get the hell out. Not everyone can, and even more just won't, leading to many of the socio-economic conditions you reference. While some of it is blamable on the companies, just as much is blamable on the shortsightedness of the people residing in these areas. Big corporations mean money for a while, but unless you as a community create a sustainable network of businesses to keep you employed, you are just handing the reins of your life over to the modern equivalent of the plantation owners. Sure you can always 'run away', but by doing so you've effectively ceded your home to the corporation/plantation owner's whims. But if you don't you're also wasting your time mucking around with slaves who refuse to rebel, content in lot which they've been given to toil.
(Score: 0) by Anonymous Coward on Wednesday May 02 2018, @04:59PM
The vast majority of people do not have the higher end skills where employers are willing to hire without an in-person interview. There is little these people can do unless they can afford to travel for a *possible* job, or fully move to a more promising city. So unless they can build up at minimum a few thousand in savings (probably need at least 5k really) then it isn't even possible to relocate or spend money traveling for interviews.
I know you covered this, but you also left in an "out" for the libertarian/conservative morons (I have to add morons because they aren't all stupid) around here with
The morons will cling to that and say it is the person's fault if they aren't willing to put in the effort for a better life. It ignores the reality that there truly are limited options for the majority of people.
(Score: 2, Insightful) by realDonaldTrump on Wednesday May 02 2018, @08:05AM (2 children)
If we don't get tough on the drug dealers, we are wasting our time. And that toughness includes the death penalty. Starting with the big pushers, the ones who are really killing people. The ones that will kill thousands of people during their lifetime. This is about winning a very, very tough problem and if we don't get very tough on these dealers, it is not going to happen, folks.
(Score: 2) by DeathMonkey on Wednesday May 02 2018, @06:08PM
We all know you actually mean "Drug-dealing-while-brown."
(Score: 3, Touché) by Anonymous Coward on Wednesday May 02 2018, @09:09PM
I agree. Death penalty for big pharma!