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CoolHand writes:

From Deadline.com:

In its quest to launch a hit fantasy series of the caliber of Game of Thrones, Amazon has closed a massive deal, said to be close to $250 million, to acquire the global TV rights to The Lord of the Rings, based on the fantasy novels by J.R.R. Tolkien. The streaming service has given a multi-season commitment to a LOTR series in the pact, which also includes a potential spin-off series.

The LOTR original series, a prequel to Tolkien's The Fellowship of the Ring, will be produced by Amazon Studios in cooperation with the Tolkien Estate and Trust, HarperCollins and New Line Cinema, a division of Warner Bros. Entertainment, which produced the hugely successful LOTR movie franchise.

No details about the deal were disclosed but it believed to be dwarfing any TV series pact to date with a whopping price tag attached.

Original Submission

takyon writes:

Microsoft founder Gates commits $100 million for fund, start-ups, to fight Alzheimer's

Billionaire Microsoft co-founder Bill Gates is to invest $50 million in the Dementia Discovery Fund, a venture capital fund that brings together industry and government to seek treatments for the brain-wasting disease. The investment is not part of Gates' philanthropic Bill & Melinda Gates Foundation and will be followed with another $50 million in a number of start-up ventures working in Alzheimer's research, Gates said.

With rapidly rising numbers of people suffering from Alzheimer's and other forms of dementia, the disease is taking a growing emotional and financial toll as people live longer, Gates told Reuters in an interview. "It's a huge problem, a growing problem, and the scale of the tragedy - even for the people who stay alive - is very high," he said.

Despite decades of scientific research, there is no treatment that can slow the progression of Alzheimer's. Current drugs can do no more than ease some of the symptoms. Gates said, however, that with focused and well-funded innovation, he's "optimistic" treatments can be found, even if they might be more than a decade away.

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takyon writes:

Study Suggests Women Less Likely to Get CPR From Bystanders

Women are less likely than men to get CPR from a bystander and more likely to die, a new study suggests, and researchers think reluctance to touch a woman's chest might be one reason.

Only 39 percent of women suffering cardiac arrest in a public place were given CPR versus 45 percent of men, and men were 23 percent more likely to survive, the study found. It involved nearly 20,000 cases around the country and is the first to examine gender differences in receiving heart help from the public versus professional responders.

"It can be kind of daunting thinking about pushing hard and fast on the center of a woman's chest" and some people may fear they are hurting her, said Audrey Blewer, a University of Pennsylvania researcher who led the study. Rescuers also may worry about moving a woman's clothing to get better access, or touching breasts to do CPR, but doing it properly "shouldn't entail that," said another study leader, U Penn's Dr. Benjamin Abella. "You put your hands on the sternum, which is the middle of the chest. In theory, you're touching in between the breasts."

The study was discussed Sunday at an American Heart Association conference in Anaheim.

Get touchy and save women's lives.

Also at Penn Medicine and the American Heart Association. Journal of the American College of Cardiology.

Other study mentioned in the AP article: Sexual Activity as a Trigger for Sudden Cardiac Arrest (DOI: 10.1016/j.jacc.2017.09.025) (DX)

Related study: Sex-Based Disparities in Incidence, Treatment, and Outcomes of Cardiac Arrest in the United States, 2003-2012. (DOI: 10.1161/JAHA.116.003704) (DX)

Original Submission

takyon writes:

Vault 8:

Today, 9 November 2017, WikiLeaks publishes the source code and development logs to Hive, a major component of the CIA infrastructure to control its malware.

Hive solves a critical problem for the malware operators at the CIA. Even the most sophisticated malware implant on a target computer is useless if there is no way for it to communicate with its operators in a secure manner that does not draw attention. Using Hive even if an implant is discovered on a target computer, attributing it to the CIA is difficult by just looking at the communication of the malware with other servers on the internet. Hive provides a covert communications platform for a whole range of CIA malware to send exfiltrated information to CIA servers and to receive new instructions from operators at the CIA.

Hive can serve multiple operations using multiple implants on target computers. Each operation anonymously registers at least one cover domain (e.g. "perfectly-boring-looking-domain.com") for its own use. The server running the domain website is rented from commercial hosting providers as a VPS (virtual private server) and its software is customized according to CIA specifications. These servers are the public-facing side of the CIA back-end infrastructure and act as a relay for HTTP(S) traffic over a VPN connection to a "hidden" CIA server called 'Blot'.

The code shows how the CIA could impersonate Kaspersky Lab:

According to WikiLeaks, CIA used these fake certificates to impersonate existing entities including Kaspersky Lab. "The three examples included in the source code build a fake certificate for the anti-virus company Kaspersky Laboratory, Moscow pretending to be signed by Thawte Premium Server CA, Cape Town. In this way, if the target organization looks at the network traffic coming out of its network, it is likely to misattribute the CIA exfiltration of data to uninvolved entities whose identities have been impersonated," noted WikiLeaks.

Also at The Register (follow-up).

Original Submission

iWantToKeepAnon writes:

Wired is running a story of hackers claiming to have broken Face ID on the new iPhone X.

When Apple released the iPhone X on November 3, it touched off an immediate race among hackers around the world to be the first to fool the company's futuristic new form of authentication. A week later, hackers on the actual other side of the world claim to have successfully duplicated someone's face to unlock his iPhone X—with what looks like a simpler technique than some security researchers believed possible.

On Friday, Vietnamese security firm Bkav released a blog post and video showing that—by all appearances—they'd cracked Face ID with a composite mask of 3-D-printed plastic, silicone, makeup, and simple paper cutouts, which in combination tricked an iPhone X into unlocking.

On a similar note Apple has repeatedly fought working with governments to unlock phones, if the police have a dead or detained criminal what is to stop them from just pointing the phone at their face and getting all the juicy data bits inside? Does Face ID *help* police/governments?

Original Submission

takyon writes:

Scientists Just Found a Vital Missing Link in The Origins of Life on Earth

Researchers from The Scripps Research Institute in California have identified a molecule capable of performing phosphorylation in water, making it a solid candidate for what has until now been a missing link in the chain from lifeless soup to evolving cells. In the classic chicken and egg conundrum of biology's origins, debate continues to rage over which process kicked off others in order to get to life. Was RNA was[sic] followed by protein structures? Did metabolism spark the whole shebang? And what about the lipids?

No matter what school of abiogenesis you hail from, the production of these various classes of organic molecules requires a process called phosphorylation – getting a group of three oxygens and a phosphorus to attach to other molecules.

Nobody has provided strong evidence in support of any particular agent that might have been responsible for making this happen to prebiotic compounds. Until now. "We suggest a phosphorylation chemistry that could have given rise, all in the same place, to oligonucleotides, oligopeptides, and the cell-like structures to enclose them," says researcher Ramanarayanan Krishnamurthy.

Enter diamidophosphate (DAP). Combined with imidazole acting as a catalyst, DAP could have bridged the critical gap from early compounds such as uridine and cytidine. That might not seem overly exciting, but phosphorylating nucleosides like these is a crucial step on the road to building the chains of RNA that could serve as the first primitive genes.

Also at Newsweek. Diamidophosphate.

Phosphorylation, oligomerization and self-assembly in water under potential prebiotic conditions (DOI: 10.1038/nchem.2878) (DX)

Related: Life's First Molecule Was Protein, Not RNA, New Model Suggests

Original Submission

takyon writes:

Gene therapy's new hope: A neuron-targeting virus is saving infant lives

Evelyn's older sister Josephine had spinal muscular atrophy type 1 (SMA1), a genetic disease that gradually paralyzes babies. She died at 15 months. Evelyn was an unexpected pregnancy, but her parents decided to have the baby despite one-in-four odds of a second tragedy.

Soon after Evelyn was born in December 2014, they were devastated to learn from genetic testing that she, too, had SMA1. "We knew what we were dealing with: We'll love her for as long as we can," says her father, Milan Villarreal. But that same night, frantically searching the internet, they learned about a clinical trial in Ohio and sent an email. At 8 weeks old, Evelyn received a gene therapy treatment that gave her body a crucial missing protein.

And now here she is, not so different from any healthy toddler. Although she has weak thighs and can't run normally or jump, she can walk quickly, dance, trace letters, toss foam blocks, carry a small chair, and climb onto her mother Elena's lap. After the heartbreak of losing their first baby, the Villarreals have watched in amazement as Evelyn has crawled, walked, and talked. "It was just a miracle. Every milestone was like a celebration. We opened a bottle of wine for every little thing she did," Milan says.

The results of the trial Evelyn participated in have blown away gene therapy researchers, too, marking one of the once-troubled field's most dramatic successes yet. All 15 babies treated for SMA1, expected to die by age 2, are alive at 20 months or older, and most can sit up, according to a report this week in The New England Journal of Medicine (NEJM). Like Evelyn, one boy is walking. Although a drug recently approved for SMA1 has achieved similar effects, it must be injected into the spine every 4 months. The gene therapy is intended as a one-time treatment, and it is simply infused into a vein. "I've never seen an effect [of gene therapy] that good in a lethal disease," says neurologist Jerry Mendell of Nationwide Children's Hospital in Columbus, who led the recent trial.

Spinal muscular atrophy.

Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy (DOI: 10.1056/NEJMoa1706198) (DX)

Related: Antisense rescues babies from killer disease (DOI: 10.1126/science.354.6318.1359) (DX)

Original Submission

MrPlow writes:

Submitted via IRC for OneLitreIn

Not all conversations with your mom about condoms have to end in mortification. For example: One mother and son turned a quip about rubbers into an industrious new way to save wine.

The Wine Condom, which is literally a condom stretched over the top of a wine bottle, was conceived by Laura Bartlett and her clearly well-adjusted son, Mitch Strahan.

The Dallas duo came up with the idea in 2014 after Bartlett sealed off a bottle of wine with plastic wrap secured with a rubber band. They realized it looked like a condom and their dream was born.

Their original contraption first launched that late spring/early summer. Recently, the two announced a new design for their invention, which works for different sizes of wine bottles. (Expect to see a few floating around at White Elephant Gift Exchange this holiday season.)

The device, made from food-grade silicone and sold online for $10 per six-pack, works much as you'd expect: After opening a bottle of wine, the Wine Condom can be rolled over the opening, creating a seal that prevents air from escaping.

Source: http://nypost.com/2017/11/10/forget-bottle-stoppers-wine-condoms-will-save-your-booze/

Original Submission

stretch611 writes:

Android is 10 years old this week. In part one of a larger story, The Register looks at the beginnings of Android, including some early competition, and a brief comparison to Microsoft.

Google was in the game, at a time when others didn't realize what the game was. Or did, and couldn't turn the ship around fast enough. Android succeeded because it was just about good enough, and its parent was prepared to cross subsidize it hugely. Android wasn't brilliant, but it was better than Bada, and uglier than WebOS. Symbian simply wasn't competitive. If you were a Samsung or Sony or HTC, then Android gave you what you needed, it gave users a better experience. Developers were happy writing for a Java OS, it was a doddle after writing for WM and Symbian.

[...] Motorola also had a significant part to play in Android's success . . . as did Verizon. Carriers like Verizon had been snubbed by Apple's carrier exclusive strategy, and Verizon was badly burned by the BlackBerry Storm. It went all in.

[...] Android is far bigger and far more invasive than a PC could ever be. Google's dominance over our personal lives is far greater than Microsoft's ever was. The clunky laptop in the corner did not track your every movement or read your emails.

Original Submission

MrPlow writes:

Submitted via IRC for SoyCow1984

When Adele fans went online to buy tickets to the pop superstar's world tour last year, they had no idea what exactly they were up against.

An army of tech-savvy resellers that included a little-known Canadian superscalper named Julien Lavallée managed to vacuum up thousands of tickets in a matter of minutes in one of the quickest tour sellouts in history.

The many fans who were shut out would have to pay scalpers like Lavallée a steep premium if they still wanted to see their favourite singer.

An investigation by CBC/Radio-Canada and the Toronto Star, based in part on documents found in the Paradise Papers, rips the lid off Lavallée's multimillion-dollar operation based out of Quebec and reveals how ticket website StubHub not only enables but rewards industrial-scale scalpers who gouge fans around the world.

CBC News obtained sales records from three U.K. shows that provide unprecedented insight into the speed and scale of Lavallée's ticket scam.

Despite a four-ticket-per-customer limit, his business snatched up 310 seats in 25 minutes, charged to 15 different names in 12 different locations.

The grand total? Nearly $52,000 worth of tickets at face value.

Source: http://www.cbc.ca/news/business/paradise-papers-stubhub-1.4395361

Original Submission

takyon writes:

Scientists have used the Spitzer Space Telescope to find a possible exoplanet or brown dwarf candidate, OGLE-2016-BLG-1190Lb, around 22,000 light years away near the center of the Milky Way galaxy. Spitzer is currently using transit photometry and gravitational microlensing to find exoplanets, a use the telescope wasn't originally designed for. Spitzer recently discovered five of the seven exoplanets around TRAPPIST-1 using the transit photometry method.

OGLE-2016-BLG-1190Lb is likely to be the first exoplanet Spitzer has found in the Milky Way's Galactic bulge using gravitational microlensing. At an estimated 13.4 ± 0.9 Jupiter masses, the object is right near the deuterium burning limit, the boundary dividing large gas giants from brown dwarfs.

The paper explains the significance of the discovery:

The discovery of Spitzer microlensing planet OGLE-2016-BLG-1190Lb is remarkable in five different respects. First, it is the first planet in the Spitzer Galactic-distribution sample that likely lies in the Galactic bulge, which would break the trend from the three previous members of this sample. Second, it is precisely measured to be right at the edge of the brown dwarf desert. Since the existence of the brown dwarf desert is the signature of different formation mechanisms for stars and planets, the extremely close proximity of OGLE-2016-BLG-1190Lb to this desert raises the question of whether it is truly a "planet" (by formation mechanism) and therefore reacts back upon its role tracing the Galactic distribution of planets, just mentioned above. Third, it is the first planet to enter the Spitzer "blind" sample whose existence was recognized prior to its choice as a Spitzer target. This seeming contradiction was clearly anticipated by Yee et al. (2015b) when they established their protocols for the Galactic distribution experiment. The discovery therefore tests the well-defined, but intricate procedures devised by Yee et al. (2015b) to deal with this possibility. Fourth, it is the first planet (and indeed the first microlensing event) for which the well-known microlens-parallax degeneracy has been broken by observations from two satellites. Finally, it is the first microlensing planet for which a complete orbital solution has been attempted. While this attempt is not completely successful in that a one-dimensional degeneracy remains, it is an important benchmark on the road to such solutions.

Also at Newsweek and BGR.

OGLE-2016-BLG-1190Lb: First Spitzer Bulge Planet Lies Near the Planet/Brown-Dwarf Boundary

Related: Seven Earth-Sized Exoplanets, Including Three Potentially Habitable, Identified Around TRAPPIST-1
Scientists Improve Brown Dwarf Weather Forecasts

Original Submission

An Anonymous Coward writes:

In Da Nang Vietnam, Australia and 10 other countries have tried to revive the TPP without the US.

Even though the analysis of the TPP has shown that the so called 'free trade agreement' has only minimal benefits and many drawbacks for developed nations the Australian Prime Minister is still set on having the agreement ratified. The Australian Prime Minister may be trying to push through the TPP before his government collapses due to the citizenship audit which is rapidly culling members of his party which could result in his party losing power in parliament. With the majority of the Australian public being against the TPP and with Malcolm Turnbull facing an election soon the reasons for this move to try to ratify the TPP is unknown.

If this trade agreement is accepted it will be the last in a series of detrimental trade agreements where Australia is on the wrong end of the stick. With Australia still reeling from the impact of the terrible China-Australia Free Trade Agreement the move to try to bring in another bad trade agreement may spell the end of the liberal government's long run in parliament.

Original Submission

MrPlow writes:

Submitted via IRC for SoyCow1984

Antivirus programs, in many cases, make us safer on the Internet. Other times, they open us to attacks that otherwise wouldn't be possible. On Friday, a researcher documented an example of the latter—a vulnerability he found in about a dozen name-brand AV programs that allows attackers who already have a toehold on a targeted computer to gain complete system control.

AVGater, as the researcher is calling the vulnerability, works by relocating malware already put into an AV quarantine folder to a location of the attacker's choosing. Attackers can exploit it by first getting a vulnerable AV program to quarantine a piece of malicious code and then moving it into a sensitive directory such as C:\Windows or C:\Program Files, which normally would be off-limits to the attacker. Six of the affected AV programs have patched the vulnerability after it was privately reported. The remaining brands have yet to fix it, said Florian Bogner, a Vienna, Austria-based security researcher who gets paid to hack businesses so he can help them identify weaknesses in their networks.

Bogner said he developed a series of AVGater exploits during several assignments that called for him to penetrate deep inside customer networks. Using malicious phishing e-mails, he was able to infect employee PCs, but he still faced a significant challenge. Because company administrators set up the PCs to run with limited system privileges, Bogner's malware was unable to access the password database—known as the Security Account Manager—that stored credentials he needed to pivot onto the corporate network.

"With the help of AVGater, I gained local admin privileges," Bogner wrote in an e-mail. With full control over the employee computer his exploit provided, he had no trouble accessing the credential store, which is commonly known as a SAM database. "So AVGater was VERY useful during several of our pentests and red-teaming assignments."

Source: https://arstechnica.com/information-technology/2017/11/how-av-can-open-you-to-attacks-that-otherwise-wouldnt-be-possible/

Original Submission

canopic jug writes:

Amos Yee is set to give his first ever public talk at Harvard.

Yee is a teenager from Singapore who has recently been granted political asylum in the US. He was in trouble with the Singaporean regime for repeatedly criticizing the country's late founder, Lee Kuan Yew. His treatment has been marginally better in the US. Although he was granted asylum by the US back in March, he was held in US jail until late September where he ran in to difficulties for his ongoing criticism of Islam. Currently, he is banned from Facebook for alleged, unspecified "community standards" violations. His videos are available on YouTube.

Original Submission

The BBC and many other sources report:

The US car industry will be wrecked if President Trump relaxes emissions standards, California's governor says.

Jerry Brown said China would dominate car manufacture because it was heavily promoting the electric vehicles that would dominate the future.

He said huge investment was needed on electric vehicles, along with federal rules to encourage their purchase.

He said President Trump and US car-makers were "half asleep" and hadn't understood the scale of the challenge.

He told BBC Radio 4's Costing the Earth: "There will be a serious threat to the US auto industry.

Unlike many in Silicon Valley, Gov. Brown seems to want the USA car industry to survive this Chinese nationally supported onslaught.

While not specifically mentioned in the article, China is working on cars at all price points, not just early adopters that can afford a Tesla or other luxury car. The Chinese stuff may be junk now (think about the batteries in Chinese "hoverboards") but it won't be for long, they learn fast. Here's a little minivan that's headed to production, https://carnewschina.com/2017/09/28/new-photos-sinogold-gm3-electric-mpv-china/

Original Submission